Table 2.
Multivariable logistic regression model for the composite outcome (n = 111) of death (n = 101) or acute dialysis (n = 17)
| Variablea | Odds Ratio (95% CI) | P |
|---|---|---|
| Log10 IL-18 (IQR: 0.71) | 1.86 (1.31 to 2.64) | <0.001 |
| Age (IQR: 25 years) | 1.48 (1.03 to 2.14) | 0.036 |
| Modified APACHE II (IQR:11 units) | 2.36 (1.58 to 3.55) | <0.001 |
| Sepsis at enrollment | 1.89 (1.06 to 3.37) | 0.031 |
| Log10 SCr (IQR: 0.70) | 1.18 (0.91 to 1.52) | 0.221 |
| Location | 0.005 | |
| SICU:MICU | 0.29 (0.14 to 0.61) | |
| Trauma:MICU | 0.79 (0.37 to 1.69) | |
| Organ failure | 1.12 (0.61 to 2.05) | 0.71 |
| Overall model | <0.001 |
a
Continuous variables ORs are represented for IQR difference (SCr and IL-18 were log10 transformed in the model). ORs are adjusted for all variables shown.