Table 1.
Overall |
P | Propensity-Matched |
SDi | |||
---|---|---|---|---|---|---|
IHD (n = 470) | CRRT (n = 266) | IHD (n = 158) | CRRT (n = 158) | |||
Patients, n (%) | ||||||
Age (years; mean [SD]) | 65.7 (15.0) | 63.7 (14.5) | 0.08 | 65.2 (14.3) | 65.6 (13.6) | 2.9 |
Male | 314 (66.8) | 180 (67.7) | 0.82 | 99 (62.7) | 116 (73.4) | 23.2 |
Body mass index (mean [SD]) | 26.5 (5.2) | 26.9 (5.5) | 0.37 | 27.1 (5.7) | 26.9 (5.3) | 3.6 |
SAPS II score (SD) | 56.3 (19.6) | 65.6 (22.3) | <0.0001 | 59.0 (20.7) | 61.7 (22.0) | 12.6 |
Number of organ failure (mean [SD]) | 2.2 (1.2) | 2.9 (1.1) | <0.0001 | 2.5 (1.1) | 2.5 (1.1) | 0 |
McCabe score (mean [SD]) | 1.4 (0.7) | 1.6 (0.7) | <0.003 | 1.6 (0.8) | 1.5 (0.7) | 13.3 |
Ventilated (mean [SD]) | 289 (61.5) | 237 (89.1) | <0.0001 | 128 (81.0) | 132 (83.5) | 6.6 |
Coma Glasgow scale (mean [SD]) | 11.4 (4.9) | 10.1 (5.3) | <0.002 | 11.2 (4.9) | 11.0 (5.0) | 4.0 |
Cardiac rhythm (mean [SD]) | 98 (38) | 108 (41) | <0.001 | 109.0 (38.3) | 105.3 (40.5) | 9.4 |
Arterial pressure (mmHg; mean [SD]) | 70.4 (28.2) | 59.1 (24.9) | <0.0001 | 64.7 (26.0) | 63.1 (27.2) | 6.0 |
Days from admission to inclusion (mean [SD]) | 2.4 (5.8) | 3.1 (7.7) | 0.24 | 3.8 (5.7) | 3.7 (9.5) | 1.3 |
Body temperature (°C; mean [SD]) | 36.8 (1.9) | 36.9 (2.5) | 0.43 | 36.9 (2.1) | 37.0 (2.4) | 4.4 |
White blood cell count (cells/μl; mean [SD]) | 13,889 (9525) | 14,879 (10,037) | 0.2 | 14,479 (10,201) | 13,999 (8158) | 5.2 |
Platelets count (cells/ml; mean [SD]) | 191,190 (127,190) | 161,410 (134,740) | <0.004 | 163,030 (117,520) | 173,030 (114,990) | 8.6 |
Prothrombin rate (%; mean [SD]) | 58.3 (22.7) | 47.4 (23.5) | <0.0001 | 53.7 (22.4) | 53.8 (23.8) | 0.4 |
pH (mean [SD]) | 7.274 (0.154) | 7.227 (0.175) | <0.0005 | 7.267 (0.167) | 7.262 (0.160) | 3.1 |
Kaliemia (mmol/L; mean [SD]) | 4.7 (1.4) | 4.5 (1.2) | 0.07 | 4.54 (1.28) | 4.50 (1.18) | 4.1 |
Lactate levels (mean [SD]) | 4.3 (4.0) | 6.2 (5.1) | <0.0001 | 4.6 (3.9) | 4.7 (4.0) | 2.5 |
Bicarbonates (mean [SD]) | 17.2 (6.2) | 18.0 (7.1) | 0.16 | 18.6 (7.7) | 18.5 (6.9) | 1.4 |
Urea (mmol/L; mean [SD]) | 24.6 (15.6) | 17.7 (10.6) | <0.0001 | 19.8 (13.0) | 19.6 (11.8) | 1.6 |
Serum creatinine (μmol/L; mean [SD]) | 366.9 (304.7) | 252.6 (144.4) | <0.0001 | 256.8 (154.8) | 267.9 (158.0) | 7.1 |
Urine output (ml/d; mean [SD]) | 991 (1009) | 826 (924) | <0.03 | 962 (768) | 922 (942) | 4.7 |
Hematocrit (%; mean [SD]) | 30.8 (8.3) | 29.9 (8.2) | 0.15 | 31.0 (8.3) | 31.2 (8.0) | 2.5 |
Hemoglobin (g/dl: mean [SD]) | 10.36 (2.90) | 10.13 (3.29) | 0.37 | 10.36 (2.64) | 10.33 (2.58) | 1.5 |
Received systemic antibiotics (n [%]) | 247 (52.6) | 205 (77.1) | <0.0001 | 116 (73.4) | 115 (72.8) | 4.1 |
Vasopressive support | 274 (58.3) | 216 (81.2) | <0.0001 | 106 (67.1) | 109 (69.0) | 4.1 |
Immunosuppression | 86 (18.3) | 41 (15.4) | 0.32 | 31 (19.6) | 21 (13.3) | 17.1 |
Diabetes | 131 (27.9) | 61 (22.9) | 0.15 | 45 (28.5) | 41 (26.0) | 5.7 |
Hypertension | 238 (50.6) | 120 (45.1) | 0.15 | 81 (51.3) | 80 (50.6) | 1.3 |
Catheter (n [%]) | ||||||
Antiseptic-impregnated catheter | 150 (31.9) | 11 (4.1) | <0.0001 | 10 (6.3) | 10 (6.3) | 0 |
catheter site | ||||||
Femoral (versus jugular) | 232 (49.4) | 138 (51.9) | 0.52 | 74 (46.8) | 85 (53.8) | 14.0 |
Days of insertion | ||||||
Mean (SD) | 6.3 (6.2) | 6.6 (6.0) | 0.53 | 8.6 (7.9) | 7.2 (6.0) | 20.0 |
Median (IQR) | 5 (2 to 8) | 5 (2 to 9) | 0.31 | 6 (3 to 11) | 6 (3 to 10) | NA |
Conditional probability to receive IHD | ||||||
Mean (SD) | 0.76 (0.23) | 0.42 (0.23) | <0.0001 | 0.54 (0.19) | 0.53 (0.20) | NA |
Median (IQR) | 0.83 (0.60 to 0.95) | 0.40 (0.24 to 0.59) | <0.0001 | 0.52 (0.40 to 0.65) | 0.52 (0.40 to 0.66) | NA |
Sdi, standardized difference; NA, not applicable.