Table 5.
Allopurinol effect in inflammatory parameters
| hsPCRa (mg/L) | C Cystatinb (mg/L) | Albuminuria (mg/d) | Fibrinogen (mg/dl) | |
|---|---|---|---|---|
| Control group | ||||
| Basal | 3.4 (5.2) | 2.0 ± 0.7 | 32 (383) | 384 ± 104 |
| 6 months | 3.0 (7.6) | 2.0 ± 0.8 | 43 (417) | 373 ± 112 |
| 12 months | 3.2 (10.8) | 1.9 ± 1.0 | 51 (296) | 402 ± 98 |
| Allopurinol group | ||||
| Basal | 4.4 (4.5) | 1.9 ± 0.5 | 36 (388) | 381 ± 78 |
| 6 months | 3.0 (4.0)c | 1.8 ± 0.6 | 15 (103) | 367 ± 58 |
| 12 months | 3.0 (2.5)c | 1.4 ± 0.4 | 16 (166) | 369 ± 49 |
a
P = 0.018 between groups and time periods (two-way ANOVA).
b
P = 0.008 between groups (two-way ANOVA).
c
P = 0.04 differences in comparison to baseline period in allopurinol group.
Data are expressed as mean ± SD or median (interquartile range). No differences were observed in hemoglobin, ESR, and serum albumin levels between groups and periods.