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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Jun 8;20(15):4531–4534. doi: 10.1016/j.bmcl.2010.06.029

Figure 1. Scaffold ranking.

Figure 1

(A) Lanes from Tris-Tricine-SDS gels showing recombination reactions in the presence of the small molecule mixtures at 10 μg/ml in bent-L recombination. “Sub” refers to the double radioactive end-labeled DNA substrate which recombines with an unlabeled partner to generate products, “Prod”. “CPD” refers to covalent protein-DNA complexes and “HJ” is the Holliday junction. (B) Quantitation of the reactions shown in Figure 1A for HJ accumulation (left Y-axis) and concurrent reduction in the formation of recombinant products (right Y-axis). Int and IHF are the proteins performing the recombination reaction.