Effects of tazobactam on pSLA induced by 3 mM glutamate (3A) or 3 mM cocaine (3B). Planarians were treated for 5 min with glutamate or cocaine by itself or in combination with tazobactam. Data are expressed as mean pSLA ± S.E.M. versus concentration of tazobactam. Main effects are indicated on the panels. **p < 0.01, *p < 0.05 compared to the glutamate or cocaine alone group (i.e., tazobactam concentration of 0 mM) following identification of significant main effects for the tazobactam/glutamate [F(4, 35) = 30.52, p < 0.0001] and tazobactam/cocaine [F(4, 35) = 21.46, p < 0.0001] data sets. N = 8 planarians per group.