Table 4.
In Vitro Inhibition of pf-HDAC1 by tricyclic ketolide-based HDACi
| Compound | n | IC50 (nM) |
|---|---|---|
| 15a | 1 | 36±2.9 |
| 15b | 2 | 10±0.5 |
| 15c | 3 | 40±1.8 |
| 15d | 4 | 290±16 |
| 15e | 5 | 304±17 |
| SAHA | - | 130±9.2 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.