Table 3. Discordant twin pairs.
| CLINICAL COHORT | REGISTER COHORT | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| AD | VaD | All dementias | All dementias | ||||||
| MZ + DZ | MZ | MZ + DZ | MZ | MZ + DZ | MZ | MZ + DZ | MZ | ||
| CVD | Tot number of twin pairs, N | 20 | 7 | 26 | 6 | 63 | 18 | 195 | 58 |
| Dementia in twin with CVD, N (%) | 11 (55) | 4 (57) | 20 (77) | 6 (100) | 41 (65) | 12 (67) | 110 (56) | 37 (64) | |
| Dementia in twin without CVD, N (%) | 9 (45) | 3 (43) | 6 (23) | 0 (0) | 22 (35) | 6 (33) | 85 (44) | 21 (36) | |
| MI | Tot number of twin pairs, N | 11 | 3 | 18 | 6 | 37 | 13 | 131 | 39 |
| Dementia in twin with MI, N (%) | 7 (64) | 2 (67) | 16 (89) | 6 (100) | 26 (70) | 9 (69) | 69 (53) | 27 (69) | |
| Dementia in twin without MI, N (%) | 4 (36) | 1 (33) | 2 (11) | 0 (0) | 11 (30) | 4 (31) | 62 (47) | 12 (31) | |
Total number of twin pairs discordant for both CVD and dementia and the distribution of dementia within the pair.
Abbreviations: AD, Alzheimer's disease; VaD, vascular dementia; MZ, monozygous twin pairs; DZ, dizygous twin pairs; CVD, cardiovascular disease; MI, myocardial infarction.