Table 4. Odds ratios from co-twin control analyses.
| CLINICAL COHORT | REGISTER COHORT | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AD | VaD | All dementias | All dementias | |||||||||||||
| MZ + DZ | MZ | MZ + DZ | MZ | MZ + DZ | MZ | MZ + DZ | MZ | |||||||||
| HRs | 95% CI | HRs | 95% CI | HRs | 95% CI | HRs | 95% CI | HRs | 95% CI | HRs | 95% CI | HRs | 95% CI | HRs | 95% CI | |
| CVD | 1.22 | (0.51-2.95) | 1.33 | (0.30-5.96) | 3.33 | (1.34-8.30) | Non-est* | 1.86 | (1.11-3.13) | 2.00 | (0.75-5.33) | 1.29 | (0.98-1.72) | 1.76 | (1.03-3.01) | |
| MI | 1.75 | (0.51-5.98) | 2.00 | (0.18-22.06) | 8.00 | (1.84-34.79) | Non-est* | 2.36 | (1.17-4.78) | 2.25 | (0.69-7.31) | 1.11 | (0.79-1.57) | 2.25 | (1.14-4.44) | |
Odds ratios (OR) with 95% confidence interval (CI) by dementia subtype and zygosity groups.
*
Among identical twin pairs, no twin without CVD developed VaD which makes it impossible to estimate an OR. Abbreviations: AD, Alzheimer's disease; VaD, vascular dementia; MZ, monozygous twin pairs; DZ, dizygous twin pairs; CVD, cardiovascular disease; MI, myocardial infarction.