Skip to main content
. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Mucosal Immunol. 2010 Jun 16;3(5):475–486. doi: 10.1038/mi.2010.31

Figure 3. Antibody responses.

Figure 3

Immunization schedule was completed as described for figure 1, and samples were analyzed for IgG1 and IgG2a M/M2-specific antibody responses by kinetic ELISA in serum 3 days prior to challenge and 7 days following challenge (a). Antibody was measured in mucosal secretion 7 days after nasal challenge with RSV. All immunized and empty vector-immunized mice were infected with RSV. Post-challenge IgG1 and IgG2a M/M2-specific antibody responses are shown for bronchoalveolar lavage (b), nasal wash (c) and vaginal washes (d).

NS=p>0.05; * p≤0.01; ** p≤0.001; *** p≤0.0001 by one-way ANOVA and T-test compared to empty vector-immunized control group. N=5 mice per group at each time point.