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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Mucosal Immunol. 2010 Jun 16;3(5):475–486. doi: 10.1038/mi.2010.31

Figure 5. Potency of T cell induction by HPV PsV-encapsidated DNA.

Figure 5

CB6F1/J mice were immunized IVag with 5×107 IU HPV16-PsV-M/M2 or 50 μg naked M/M2 DNA. Negative control mice received 5×107 IU HPV16 PsV-luciferase. All mice were challenged IN with RSV at week 4. DbM187–195 (red) and KdM282–90-specific (blue) CD8+ T cells were detected by tetramer staining in lungs on day 7 post-challenge. * = p≤0.01 and ** = p≤0.001 by one-way ANOVA and T-test compared to empty vector-immunized mice. N=5 mice per group from one independent experiment.