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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Mucosal Immunol. 2010 Jun 16;3(5):475–486. doi: 10.1038/mi.2010.31

Figure 6. Induction of IgG by HPV-encapsidated DNA.

Figure 6

Following immunization with a single dose of HPV16 PsV-encapsidated M/M2-expressing DNA, naked M/M2-expressing DNA or empty HPV16 PsV capsids M/M2-specific IgG1 and IgG2 levels were evaluated by kinetic ELISA in serum 3 days prior to challenge (a). RSV M/M2-specific IgG isotypes were also measured in BAL (b), nasal washes (c), and vaginal washes (d) on day 12 post-challenge. Total IgG was measured by ELISA in both nasal and vaginal washes (c and d, panels on far right). P values are derived from one-way ANOVA (NS =p>0.05; + ≤0.05; * ≤0.01; ** ≤0.001; *** ≤0.0001). The data represent each individual sample from each animal from one independent experiment.