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Activating transcription factor 3 (ATF3) immunoreactivity in hypospadic and control tissues (×100). (A) There is no ATF3 immunoreactivity in circumcision control tissue. (B) ATF3 is clearly expressed in the nucleous of the cell (arrow) in the sc tissue of subcoronal hypospadic sample. (C) ATF3 protein localized in the nuclei of stromal cells (black arrow) and the vascular endothelium (white arrow) in sc tissue of mid penil hypospadic sample.
