Figure 2c-d.

Dasatinib treatment inhibits cell proliferation and migration and disrupts cytoskeletal organization. (c). Transwell migration analysis was performed with or without dasatinib (100 nM) as described in the Materials and Methods. At the end of the experiment, cells on the lower part of the membrane was fixed, stained, and images were taken. (d) Migrated cells were counted as described in the Materials and Methods. Glioma cells incubated with dasatinib (100 nM) showed 40-90% reduction in migration through pores compared with untreated control cells