Figure 3a-c.

Inhibition of Src and STAT3 signaling suppresses glioma cell growth and migration. (a) The relationship between specific siRNA or mock transfection and cell numbers was assessed semiquantitatively by spectrophotometric measurement of MTS bioreduction. (b) U87 and T98G cells were transfected with indicated siRNA. Cell migration assay was performed as described in Materials and Methods and representative images were shown. (c) Migrated cells were presented as a percentage of mock-transfected control. **P< 0.05, combination of Src and STAT siRNA versus individual siRNA