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. Author manuscript; available in PMC: 2010 Aug 20.
Published in final edited form as: Methods Enzymol. 2004;384:212–232. doi: 10.1016/S0076-6879(04)84013-8

Figure 1.

Figure 1

Schematic illustraiton of specific and nonspecific hetero-interactions. A) Discrete binding with A+2B → AB2 model. B) Nonspecific binding of a large ligand to a finite, one-dimensional lattice. One of the 6 possible configurations for binding of two ligands of length 4 to a linear lattice of length 10. The open circles represent lattice sites. C) Overlapping ligand model for the nonspecific binding of two ligands of length 4 to a helical lattice of length 10 with a minimal offset of 2. The leftmost binding site on the ligand must contact a lattice site indicated by an open circle. Only one of the 15 possible configurations is shown.