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. Author manuscript; available in PMC: 2010 Aug 20.
Published in final edited form as: Cancer Gene Ther. 2008 Oct 10;16(3):266–278. doi: 10.1038/cgt.2008.74

Figure 4. Enhanced tumor response in rats treated with rVSV-UL141 versus those treated with rVSV-F.

Figure 4

Multi-focal HCC-bearing Buffalo rats were injected via the hepatic artery with PBS (n=3), rVSV-F (n=4) or rVSV-UL141 (n=4) at 1×107 pfu/rat and sacrificed 3 days post-treatment. Panel A, 5 µm tumor sections were stained with H&E. Representative sections from rats treated with PBS, rVSV-F and rVSV-UL141 are shown in frames a, b and c, respectively (magnification=40×). Panel B, Percentage of necrotic areas in the tumors were measured morphometrically using ImagePro software. Data are shown as mean ± standard deviation, and the results were analyzed statistically by two-sided student t test.