Table 1.
Summary of ALDH3B1 immunoreactivity in normal human tissues
| Human tissuea | ALDH3B1 immunoreactivity | Cell type | Localization |
|---|---|---|---|
| Bone marrow | + | Histiocytes | Cytoplasm |
| Cerebellum | + | Astrocytes, molecular layer of gray matter | ND |
| Colon | − | NA | NA |
| Endometrium | + | Few histiocytes | Cytoplasm |
| Kidney cortex | + | Proximal convoluted tubule cells | Cytoplasm |
| Kidney medulla | + | Loop of Henle cells | Cytoplasm |
| + | Collecting duct cells | Membrane-associatedb | |
| Liver | + | Hepatocytes | Cytoplasm |
| Lung | + | Ciliated brionchiole epithelial cells | Membrane-bound/associatedc |
| Ovary | − | NA | NA |
| Placenta | + | Intermediate trophoblasts | Cytoplasm |
| Pancreas | + | Acinar cells | Cytoplasm |
| Salivary gland | + | Striated duct cells | Membrane-associatedb |
| Spleen | + | Sinusoidal endothelial cells of red pulp | Cytoplasm |
| Testis | + | Ciliated columnar efferent ductule cells | Membrane-bound/associatedc |
| Thyroid | + | Few histiocytes | cytoplasm |
a
Human tissues immunoreactive (+) and non-immunoreactive (−) for ALDH3B1 are listed.
b
In kidney medulla and salivary gland, staining of duct cells appeared cytoplasmic but was stronger on the luminal surface of ducts, indicating a potential membrane association.
c
In lung and testis, staining was limited to cilia on the apical surface of cells; it was unclear whether localization was membrane-bound or cytoplasmic but membrane-associated.
NA, not applicable; ND, not determined.