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Protein structure of CFTR and target regions of anti-pCFTR antibodies. Two different epitopes (stars) were selected for generating anti-pCFTR antibodies pCFTR-N (corresponding to aa 410–423, EKAKQNNNSRKISN) and pCFTR-C (corresponding to aa 1451–1464, LLPHRNSSKQRSRS). pCFTR, porcine cystic fibrosis transmembrane conductance regulator; NBD, nucleotide-binding domain; R, regulatory domain; MSD, membrane-spanning domain. Drawn using a description from the CFTR database.
