TABLE II.
Frequency of 5-HTTLPR and CRHR1 Genotypes
| 5-HTTLPR genotype | 5-HTTLPR genotype and rs25531 | |||||
|---|---|---|---|---|---|---|
| Functional classification [Hu et al., 2006] | ||||||
| N | % | N | % | |||
| LL | 598 | 55.78 | LALA | 292 | 27.2 | High |
| LALG | 269 | 25.1 | Intermediate | |||
| LGLG | 37 | 3.5 | Low | |||
| SL | 359 | 33.49 | SLA | 243 | 22.7 | Intermediate |
| SLG | 116 | 10.8 | Low | |||
| SS | 66 | 6.16 | 66 | 6.2 | Low | |
| LXL | 35 | 3.26 | LAXL | 20 | 1.9 | |
| LGXL | 15 | 1.4 | ||||
| SXL | 8 | 0.75 | 8 | 0.8 | ||
| LVL | 6 | 0.56 | LAVL | 3 | 0.3 | |
| LGVL | 3 | 0.3 | ||||
| N total | 1,072 | 1,072 | ||||
| CRHR1 rs110402 | CRHR1 TCA haplotype | ||||
|---|---|---|---|---|---|
| N | % | N | % | ||
| AA | 87 | 7.2 | 0 allele | 577 | 48.8 |
| AG | 544 | 44.8 | 1 allele | 519 | 43.9 |
| GG | 582 | 48.0 | 2 alleles | 87 | 7.3 |
| N total | 1,234 | ||||
| SERT*TCA haplotype risk | ||
|---|---|---|
| N | % | |
| No risk alleles | 286 | 24.2 |
| S-allele only | 214 | 18.1 |
| CRHR1 risk only | 293 | 24.8 |
| Both risk alleles | 195 | 16.5 |