Table 2.
Host proteins selectively co-purifying with HIV-1 PICs
| Host Proteins | Accession numbers | Molecular Weight | No. of peptides |
|---|---|---|---|
| Chromatin organization | |||
| Barrier-to-autointegration factor | baf_bovin | 10 kDa | 3 |
| Nucleosome assembly protein 1-like 1 | np1l1_bovin | 45 kDa | 5 |
| Histone-binding protein RBBP4 | rbbp4_bovin | 48 kDa | 3 |
| Transcription regulation | |||
| Acidic leucine-rich nuclear phosphoprotein 32 family member A | an32a_bovin | 29 kDa | 4 |
| Acidic leucine-rich nuclear phosphoprotein 32 family member E | an32e_human | 31 kDa | 3 |
| Calreticulin | calr_cerae | 48 kDa | 5 |
| NF-kappa-B essential modulator | nemo_bovin | 49 kDa | 7 |
| Non-POU domain-containing octamer-binding protein | nono_human | 54 kDa | 8 |
| RNA polymerase-associated protein LEO1 | leo1_human | 75 kDa | 6 |
| RNA processing/localization | |||
| ATP-dependent RNA helicase DDX19A | dd19a_bovin | 54 kDa | 4 |
| Double-stranded RNA-binding protein Staufen homolog 1 | stau1_human | 63 kDa | 2 |
| Heterogeneous nuclear ribonucleoprotein H1 | hnrh1_human | 49 kDa | 2 |
| Heterogeneous nuclear ribonucleoprotein H3 | hnrh3_human | 37 kDa | 3 |
| Plasminogen activator inhibitor 1 RNA-binding protein | pairb_human | 45 kDa | 7 |
| Splicing factor 3B subunit 2 | sf3b2_human | 98 kDa | 19 |
| Splicing factor, arginine/serine-rich 3 | sfrs3_bovin | 19 kDa | 3 |
| U4/U6.U5 tri-snRNP-associated protein 1 | snut1_human | 90 kDa | 17 |
| Translation | |||
| Eukaryotic translation initiation factor 4 gamma 1 | if4g1_human | 176 kDa | 3 |
| Cytoplasmic trafficking | |||
| Dynactin subunit 2 | dctn2_human | 44 kDa | 3 |
The host proteins have been broadly categorized based on the known physiological function. The number of peptides identified by mass spectroscopic analysis and assigned to the specific protein in the database is shown.