Table 2.
Hardy-Weinberg-Equilibrium of all SNPs analyzed in the Greifswald cohort
| CHR | SNP ID | HWE TEST | A1 | A2 | GENO | O(HET) | E(HET) | HW p-value |
|---|---|---|---|---|---|---|---|---|
| 9 | rs2891168 | ALL | G | A | 108/229/132 | 0.49 | 0.50 | 0.64 |
| 9 | rs2891168 | AFF | G | A | 34/69/27 | 0.53 | 0.50 | 0.60 |
| 9 | rs2891168 | UNAFF | G | A | 74/160/105 | 0.47 | 0.50 | 0.38 |
| 9 | rs1333042 | ALL | G | A | 111/231/125 | 0.49 | 0.50 | 0.85 |
| 9 | rs1333042 | AFF | G | A | 35/68/27 | 0.52 | 0.50 | 0.72 |
| 9 | rs1333042 | UNAFF | G | A | 76/163/98 | 0.48 | 0.50 | 0.59 |
| 9 | rs1333048 | ALL | C | A | 114/229/126 | 0.49 | 0.50 | 0.64 |
| 9 | rs1333048 | AFF | C | A | 38/65/27 | 0.50 | 0.50 | 1.00 |
| 9 | rs1333048 | UNAFF | C | A | 76/164/99 | 0.48 | 0.50 | 0.66 |
| 9 | rs496892 | ALL | T | C | 99/257/113 | 0.55 | 0.50 | 0.04 |
| 9 | rs496892 | AFF | T | C | 21/68/41 | 0.52 | 0.49 | 0.48 |
| 9 | rs496892 | UNAFF | T | C | 78/189/72 | 0.56 | 0.50 | 0.04 |
CHR: Chromosome; HWE Test: Test of the respective SNP for Hardy-Weinberg Equilibrium for all analyzed individuals (ALL), cases with gAgP (AFF), and control subjects unaffected by gAgP (UNAFF); A1: Minor allele; A2: Major allele; GENO: Genotype counts: Number of individuals homozygous for the minor allele/Number of heterozygous individuals/Number of individuals homozygous for the major allele; O(HET): Observed heterozygosity; E(HET): Expected heterozygosity; HW p-value: Hardy-Weinberg p-value.