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. 2010 Aug 20;5(8):e12278. doi: 10.1371/journal.pone.0012278

Figure 7. Increased ultrasonic vocalizations (USVs) of newborn pups with a maternal deletion (m−/p+) from Ube3a to Gabrb3.

Figure 7

A and B. Comparison of m−/p+ and m+/p− pups respectively to their m+/p+ littermates in different beddings. The m−/p+ pups emitted significantly more USVs than that of m+/p+ littermates at mother's bedding (p = 0.006) (2B) but not for m+/p− pups(2C, p>0.05). C. Comparison of USVs of m−/p+ to m+/p+ at different postnatal days. The m−/p+ pups emitted more USVs overall than m+/p+ mice but this was only statistically significantly on day 10 (p = 0.02) and day 12 (p = 0.05). The three-way (genotype X bedding X day) with mixed design ANOVA did not reveal significant interaction among them (p = 0.07). Similarly, two-way ANOVA did not reveal significant interactions between genotype and bedding (p = 0.15), and between genotype and day (p = 0.29). D. Comparison of USVs for m−/p+ and m+/p− pups recorded in clean bedding at low temperature (4–6°C) on day 10 and day 12. There was no significant difference between m−/p+ and their m+/p+ littermates (p = 0.82), or between m+/p− and their m+/p+ littermates (p = 0.3). * p<0.05.