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. 2010 Aug 20;5(8):e12290. doi: 10.1371/journal.pone.0012290

Figure 5. Effects of cPTH on bone structure and turnover in TNF −/− mice.

Figure 5

A µCT analysis of femoral Co.Th. B µCT analysis of femoral Co.Vo. C µCT analysis of BV/TV. D Serum CTX levels. E Serum OCN levels. F–J Histomorphometric analysis of femoral trabecular bone. F: percentage of bone surface covered by osteoclasts (Oc.S/BS). G: number of osteoclasts per mm bone surface (N.Oc/BS). H: Bone formation rate (BFR). I: Percentage of bone surface covered by osteoblasts (Ob.S/BS). J: Number of osteoblasts per mm bone surface (N.Ob/BS). K–L mRNA levels of RANKL and OPG in SCs from WT and TNF−/− mice treated in vivo with vehicle or cPTH. * = p<0.05 compared to the corresponding vehicle group. n = 9–15 mice per group. Data are Means + SEM.