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. Author manuscript; available in PMC: 2011 Aug 27.
Published in final edited form as: Transplantation. 2010 Aug 27;90(4):387–393. doi: 10.1097/TP.0b013e3181e6ae0a

Figure 3.

Figure 3

MPA (40 mg/kg/d × 6 months) prevented EMT in rat kidney allografts. Immunoblot analyses for syngeneic (S), allogeneic (A) and allogeneic transplants treated with MPA (Allo + MPA) demonstrated that MPA therapy was associated with significant downregulation of Nox-2 and fibrogenesis as evidenced by decreased amounts of phospho-NF-κB, phospho-smad2, fibronectin and α-SMA. All experiments were performed three times and the bar graph represents fold changes (arbitrary units using the NIH image J software) compared to GAPDH internal control from three independent experiments.