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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Int J Neuropsychopharmacol. 2010 Feb 11;13(8):997–1009. doi: 10.1017/S1461145710000039

Figure 5.

Figure 5

Effects of acute antidepressant drug treatment, given 30 min prior to the R1 reversal task. Panel A: Acute treatment with CIT (5 mg/kg, i.p.) improved performance of CIC stress-stressed rats on the R1 reversal task (*p < 0.01 compared to non-stressed control rats on the same task; +p < 0.01 compared to vehicle-treated CIC-stressed rats on the same task; mean ± SEM; n = 8 per group). Panel B: Acute treatment with DMI (5 mg/kg, i.p.) had no beneficial effect on the increased number of trials required to reach criterion on the R1 task after CIC stress, comparable to vehicle-treated CIC-stressed rats. (*p < 0.05 compared to vehicle-treated, non-stressed control rats; mean ± SEM; n = 6 per group).