Table 5.

Effect of hydroalcoholic extract of S. indicus on pentylenetetrazole (50 mg/ kg, i.p.)-induced seizures in mice

Treatment	Dose (mg/kg)	Pentylenetetrazole-induced generalized clonic seizures
		Incidence	Latency (sec)	Duration (sec)
Control	-	10/10	116.7 ± 13.6	10.4 ± 0.54
SIE	100	10/10	129.5 ± 15.2	7.2± 0.44*
SIE	200	10/10	139.8 ± 12.8	6.8 ± 0.31*
SIE	500	8/10	183.3 ± 18.9	6.6 ± 0.57*
Diazepam	4	0/10	-	-

Values are expressed as mean ± SEM (n = 10). One-way ANOVA followed by Dunnett's test

^*P < 0.05 when compared with control group