. Author manuscript; available in PMC: 2011 Oct 1.

Published in final edited form as: J Affect Disord. 2010 Apr 27;126(1-2):299–302. doi: 10.1016/j.jad.2010.03.014

Table.

Morbidity as %-of-weeks during first two years in 247 cases of first-episode DSM-IV type I bipolar disorder

Morbidity	Onset Types		Relative Risk	F-value	p-value
Morbidity	Mixed (n=97)	Mania (n=150)	Relative Risk	F-value	p-value
Mixed-states	30.8 ± 37.6	2.58 ± 12.1	11.9	73.0	<0.0001
Dysthymia	15.3 ± 23.5	9.03 ± 20.7	1.69	4.86	0.03
Major Depression	10.2 ± 18.9	1.56 ± 6.16	6.54	26.8	<0.0001
Mania	1.75 ± 2.95	18.0 ± 28.5	0.10	31.0	<0.0001
Hypomania	0.91 ± 4.01	5.50 ± 18.7	0.17	5.66	0.02
Psychosis	0.77 ± 5.29	1.04 ± 7.06	0.40	0.10	0.75
All morbidity	60.0 ± 36.9	37.8 ± 35.5	1.59	22.3	<0.0001

DSM-IV bipolar I disorder patients (N=247) were followed prospectively for 2 years from first-lifetime major episodes of mania or mixed-states, with the percent of weeks in specific morbid-states indicated, with differences between the sub-groups.