Table 3.
Predictive factors in Cox Proportionate Hazards Models, including diagnosis of dementia, age, educational level, sex, family history of dementia, CT scan findings, and vascular risk factors, for the progression of dementia (worsening of severity according to CDR scale).
Variable | Hazards ratio | CI 95% lower–upper | P-value | r |
---|---|---|---|---|
Diagnosis of dementia | 18.627 | 0.94–370.77 | .055 | 2.925 |
Age | 1.060 | 96–1.17 | .254 | 0.058 |
Sex | 0.510 | 0.13–1.96 | .327 | −0.673 |
Educational level | 1.323 | 1.10–1.59 | .002 | 0.280 |
Vascular risk factors | .329 | |||
Hypertension | 38.32 | 1.37–1070.3 | .032 | 3.646 |
Diabetes mellitus | 0.000 | 0.00–2.3E +101 | .992 | −9.928 |
Hypertension + diabetes mellitus | 28.30 | 0.74 – 1082.7 | .072 | 3.343 |
Family history of dementia | .339 | |||
Present | 0.473 | 0.09–2.62 | .392 | −0.748 |
Unknown | 0.305 | 0.05–1.81 | .191 | −1.187 |
CT findings | .985 | |||
Mild diffuse atrophy AND/OR ↑ ventricles | 547201.7 | 0.00–8.5E +111 | .919 | 13.213 |
Atrophy + leukoaraiosis | 728853.1 | 0.00–1.1E +117 | .918 | 13.499 |
Focal abnormality | 392780.9 | 0.00 –6.1E +116 | .921 | 12.881 |
Diagnosis of dementia: 0 = VaD; 1= AD.