Table 2.

Kinetic constants for mTGR using different disulfides as substrates.

Disulfide		mTGR
	Km	k cat	k cat /Km
	(μM)	(S−1)	(M−1 S−1)
Trx-S2 T. crassiceps	0.87	0.47	5.4 x 105
Trx-S2 P. falciparum	28.3	0.81	2.8 x 104
Trx-S2 H. sapiens	21.3	0.44	2.1 x 104
GSSG	41.4	0.84	2.0 x 104
DTNB	34.5	0.30	8.7 x 103

Date obtained using 100 μM NADPH at 25°C and pH 7.8.