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. Author manuscript; available in PMC: 2011 Sep 15.
Published in final edited form as: Virology. 2010 Jun 26;405(1):165–175. doi: 10.1016/j.virol.2010.05.034

Table 2.

IgG titers induced by ASC in spleen during ex-vivo culturea

Days of incubation Recombinant HA wtVLP ΔVLP none
Control Vaccine Vacc.+Ag. rechallenge Control Vaccine Vacc.+Ag. rechallenge Control Vaccine Vacc.+Ag. rechallenge naïve
day 1 b88.9±33.2 98.0±24.2 95.1±19.4 70.7±21.4 83.3±25.1 352±139 58.4±11.9 67.8±19.7 680±378 76.2±16.1
day 5 103±27.3 76.8±28.1 129±43.4 99.1±64.9 269±165 535±199 61.3±30.8 63.0±29.6 973±132 76.1±39.0
a

IgG titers induced by plasma cell determined with quantitative ELISA.

b

Values are means ± S.D. (ng/ml) of four independent ex-vivo culture plate wells.

Control: Naïve mice (n=3) with in vivo antigenic challenge 6 days earlier before sacrifice. Vaccine: Vaccinated mice (n=3) without in vivo antigenic challenge. Vacc.+Ag. rechallenge: Vaccinated mice (n=3) with in vivo antigenic challenge 6 days earlier before sacrifice.