Table 2. Cytokine secretion by BEAS-2B cells after 24h exposure with polar organic extracts from PM2.5 collected in Puerto Rico.
Cytokine concentrations (pg/ml) secreted by BEAS-2B cells treated with polar organic extracts from PM2.5 collected at two different sites (Guaynabo and Fajardo) in Puerto Rico. Results are tabulated with the SE of the mean, considered statistically significant with p<0.05 and illustrated when there is a positive (+) or a negative (-) secretion pattern in response to the exposure (n = 3).
| Treatments | IL-6 (pg/ml) |
IL-8 (pg/ml) |
MCP-1 (MCAF) (pg/ml) |
IL-1β (pg/ml) |
G-CSF (pg/ml) |
IL-7 (pg/ml) |
|---|---|---|---|---|---|---|
| Control |
119.6 (±0.5) |
274.6 (±10.5) |
45.7 (±0.2) |
<LOW> |
146.1 (±2.7) |
4.9 (±0.8) |
| 50μg/ml - Guaynabo |
649.5 (±29.7)+++ |
235.1 (±6.8)--- |
14.2 (±1.1)--- |
4.9 (±0.7)+++ |
73.3 (±2.2)--- |
9.7 (±2.4) |
| 100μg/ml - Guaynabo |
603.1 (±9.0)+++ |
134 (±1.0)--- |
11.1 (±1.4)--- |
7.7 (±0.4)+++ |
39.1 (±2.7)--- |
11.8 (±1.5)++ |
| 50μg/ml - Fajardo |
522.7 (±19.9)+++ |
221.2 (±2.1)--- |
13.0 (±0.7)--- |
2.1 (±0.2)+ |
65.3 (±0.6)--- |
6.1 (±1.4) |
| 100μg/ml - Fajardo |
577.5 (±4.2)+++ |
136.7 (±4.7)--- |
11.7 (±1.0)--- |
7.6 (±0.3)+++ |
31.9 (±0.9)+++ |
11.2 (±0.4)++ |
| 10μg/ml - LPS |
942.8 (±10.9)+++ |
1274.1 (±10.9)+++ |
88.5 (±2.9)+++ |
2.3 (±0.1)+++ |
2066 (±83.5)+++ |
12.7 (±0.7)++ |