Skip to main content
. Author manuscript; available in PMC: 2010 Aug 23.
Published in final edited form as: S Afr Med J. 2009 Oct;99(10):730–737.

Table III.

Predictors of mortality using Cox-proportional hazards model stratified by site (adjusted for year of ART start)

Characteristic at ART start Crude HR 95% CI p-value Adjusted HR
Full model
(N=2 449)
95% CI p-value
WAZ <0.001* <0.001*
 >−2 1 1
 −3 - −2 1.93 1.29 - 2.89 1.13 0.69 - 1.87
 < −3 5.23 3.84 - 7.12 2.44 1.65 - 3.59
Viral load (copies/ml) <0.001* 0.010*
 <100 000 1 1
 100 000 to 1 million 1.75 1.24 - 2.45 1.68 1.02 - 2.76
 >1 million 3.30 2.32 - 4.70 2.22 1.31 - 3.77
Severe immunosuppression
(WHO definition)
4.23 2.55 - 7.00 <0.001 3.83 1.68 - 8.72 0.001
WHO stage 3 or 4 (v. 1 or 2) 3.01 2.00 - 4.54 <0.001 2.16 1.28 - 3.62 0.004
Age <0.001* 0.002*
 >3 yrs 1 1
 1 - 3 yrs 1.31 0.98 - 1.74 1.17 0.76 - 1.84
 <1 yr 3.38 2.65 - 4.31 2.00 1.30 - 3.07
ART commenced before 2006 1.28 1.02 - 1.60 0.036 1.68 1.18 - 2.39 0.004

p-values derived from likelihood ratio tests.