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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Biomark Med. 2010 Jun;4(3):453–464. doi: 10.2217/bmm.10.14

Figure 1. The synthesis and processing of PrP from pre-pro-PrP to pro-PrP to mature, glycosylated, GPI-anchored PrP.

Figure 1

GPI: Glycosylphosphatidylinositol; LPS: Leader peptide signal sequence; N: N-linked glycans; PrP: Prion protein; PSS: Peptide signal sequence; S–S: Disulfide bridge; TM: Putative transmembrane domain.