Figure 6. Antibody-mediated targeting of ICAM-1.
(A) In order to demonstrate the versatility of UAN platform, UAN nanoparticles were encapsulated with DPA or CPT, while the surface of UAN was coated with four different combinations of protein A and mAb R6.5. HeLa cells were imaged 2 hours after incubation with UAN(DPA) and 28 hours with UAN(CPT). (B) The bar graphs were normalized to that of no protein A and no R6.5 control (‘-/-’, n=3).