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. Author manuscript; available in PMC: 2010 Aug 23.
Published in final edited form as: J Immunol. 2009 Oct 21;183(10):6313–6319. doi: 10.4049/jimmunol.0803422

Figure 2. UCP2-deficient mast cells have enhanced degranulation.

Figure 2

(A) Wild-type and Ucp2−/− BMMCs were sensitized overnight with anti-DNP IgE (100 ng/ml) and challenged for 20 min with DNP-HSA (10 ng/ml). (B) Wild-type and Ucp2−/− FSMCs were stimulated for 10 min with SP (100 μM), C48/80 (30 μg/ml), or ionomycin (1 μM), after which histamine was measured in the supernatant and pellet. *P <0.05 (n=6)

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