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. Author manuscript; available in PMC: 2011 Jul 14.
Published in final edited form as: Nano Lett. 2010 Jul 14;10(7):2543–2548. doi: 10.1021/nl101140t

Figure 2.

Figure 2

AuNP uptake and membrane potential. (A) In CP70 cells, only +AuNPs (0.4 μM) showed significant uptake, with substantial intracellular levels present at 5 min, followed by a higher level beyond 2h. (B) Prior exposure to KCl (inducing membrane depolarization) significantly (p<0.05) reduced the extent of uptake of +AuNPs (1.2 μM for 30 minutes treatment) in four different types of cells. (C) In all the cells investigated, prior exposure to KCl significantly blunted the extent of membrane depolarization subsequently induced by +AuNPs. Values are means ± SE. * indicates significant AuNP effect (p<0.05).