Table 1.

Clinical characteristics and outcomes of reported cases of thrombolysis in infective endocarditis.

Ref. no	Year	Age	Gender	IE suspected	Organism	Fever	Symptoms	Admission NIHSS Score	Imaging prior to thrombolysis	Thrombolytic used	Time interval	Microaneurysms	Discharge NIHSS score Bleeding complication
1	2003	31	F	Prethrombolysis	Streptococcus mitis	Absent	Limb weakness Vertigo Tinnitus Gaze palsies	13	CT scan: hypodensity of thalamus	Intra-arterial urokinase	5h	None on CT	NIHSS score 5, no hemorrhage
8	2009	12	F	Post thrombolysis	Streptococcus pneumoniae	Present	Acute hemiparesis Aphasia	18	MRI: multiple diffusion-restricted lesions; MRA absent flow in the left internal carotid artery	Intra-arterial t-PA	6h	None on MRI	NIHSS score 5, no hemorrhage
19	2007	56	M	Post thrombolysis	Beta-hemolytic streptococcus	Present	Acute hemiparesis Aphasia	15	CT scan: loss of insular ribbon with indistinctness of lentiform nuclei, no hypodensity	Intravenous t-PA	2h, 36 min	Unknown	NIHSS score 4, no hemorrhage
Our case	2009	70	M	Post thrombolysis	Streptococcus pneumonia	Present	Acute hemiparesis Aphasia	13	CT scan: hypodensity	Intravenous t-PA	2h, 30 min	None on MRA	NIHSS score 5, no hemorrhage

IE: infective endocarditis; M: male; F: female; NIHSS: National Institute of Health Stroke Scale; CT: computed tomography; MRI: magnetic resonance imaging; MRA: magnetic resonance angiography.