Table 2.
Comparisons of anthropometric and metabolic characteristics among 3 genotypes at rs2237892
| Genotype | P | |||
|---|---|---|---|---|
| rs2237892 | CC | CT | TT | |
| Numbers | 189 | 168 | 41 | |
| Sex, male (n/%) | 92/48.7 | 81/48.2 | 21/51.2 | 0.942 |
| Age, years | 51.04 ± 5.48 | 51.96 ± 5.50 | 52.64 ± 5.39 | 0.864 |
| Hypertension, n/% | 106/56.1 | 101/60.1 | 28/68.3 | 0.330 |
| Type 2 diabetes mellitus, n/% | 27/14.3 | 24/14.3 | 6/14.6 | 0.998 |
| Family history of CAD, n/% | 73/38.6 | 63/37.5 | 18/43.9 | 0.752 |
| Smokers, n/% | 63/33.3 | 61/36.3 | 15/36.6 | 0.818 |
| BMI, kg/m2 | 24.34 ± 3.35 | 24.89 ± 3.94 | 24.59 ± 3.00 | 0.362 |
| FBS, mmol/L | 5.73 ± 1.61 | 5.51 ± 0.94 | 6.04 ± 2.01 | 0.120 |
| Insulin, mU/L | 13.70 ± 11.28 | 13.43 ± 10.02 | 18.66 ± 13.04 | 0.232 |
| HOMA-IR | 3.68 ± 0.69 | 3.51 ± 0.59 | 4.78 ± 0.81 | 0.437 |
| TC, mmol/L | 4.60 ± 0.90 | 4.41 ± 0.90 | 4.75 ± 0.66 | 0.157 |
| TG, mmol/L | 1.60 ± 0.83 | 1.48 ± 0.74 | 2.01 ± 0.87 | 0.026 |
| LDL-C, mmol/L | 2.77 ± 0.78 | 2.72 ± 0.77 | 2.85 ± 0.82 | 0.759 |
| HDL-C, mmol/L | 1.19 ± 0.29 | 1.14 ± 0.25 | 1.09 ± 0.25 | 0.178 |
| Apo A1, g/L | 1.14 ± 0.18 | 1.08 ± 0.19 | 1.12 ± 0.18 | 0.095 |
| Apo B, g/L | 0.88 ± 0.26 | 0.85 ± 0.25 | 0.92 ± 0.21 | 0.072 |
Abbreviations see Table 1.