Table 3.
Reported actions of desacyl-ghrelin.
| Effect of desacyl-ghrelin | Compared with acylghrelin | Reference |
|---|---|---|
| shared or opposite | ||
| Adipocytes | ||
| (1) ↓ fat oxidation | ||
| (2) ↑ glucose uptake | ||
| (3) ↑ differentiation | shared | [195, 199] |
| (4) ↑ hypertrophy | ||
| (5) ↓ lipolysis | ||
| anorexigenic | opposite | [190, 196] |
| Antiapoptotic | ||
| (1) islet beta cells | shared | [22, 194] |
| (2) cardiomyocytes | ||
| antiinflammatory | shared and unshared | [188, 200] |
| body weight | opposite | [75] |
| cardioprotection | shared | [194, 201] |
| gastric motility | opposite | [196, 208] |
| ↓ hepatic gluconeogenesis | opposite | [198] |
| hypotension | shared | [197] |
| locomotion | unknown | [209] |
| ↑ insulin sensitivity | opposite | [210] |
| neurogenesis | shared | [211–214] |
| skeletal-muscle differentiation | shared | [193] |
| ↓ somatic growth | opposite | [75] |
| vascular smooth-muscle relaxation | similar | [197] |