Table 6.
Adipogenic effects of ghrelin.
| (1) decrease fat-cell lipid export |
| (2) enhance lipoprotein lipase |
| (3) reduce insulin sensitivity |
| (4) stimulate preadipocyte proliferation |
| (5) promote adipocyte differentiation |
| (6) inhibit 5′-adenosine monophosphate protein kinase (AMP-kinase) |
| (7) augment hepatic glucose output and triacylglyceride content |
| (8) activate acetyl CoA carboxylase |
| (9) inhibit fatty acid oxidation |
| (10) induce leptin, sterol-response element binding protein-1c and |
| (11) PPAR-gamma |
| (12) suppress adiponectin |
| (13) increase appetite |