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. Author manuscript; available in PMC: 2010 Aug 23.
Published in final edited form as: Curr Opin Hematol. 2009 Nov;16(6):460–465. doi: 10.1097/MOH.0b013e3283319e8f

Figure 2. Nonmyeloablative conditioning regimen of total lymphoid irradiation and antithymocyte globulin.

Figure 2

Ten doses of total lymphoid irradiation (TLI) (at 80 cGy each) given over a period of 11 days (as indicated by arrows). Antithymocyte globulin (ATG) (at a dose of 1.5 mg per kilogram of body weight per day) was administered intravenously on days −11 through −7 (as indicated by arrows). An infusion of mobilized human leukocyte antigen (HLA)-matched peripheral blood mononuclear cells from a donor was administered on day 0. Immunosuppressive therapy after transplantation included oral cyclosporine started on day −3, at a dose of 6.25 mg per kilogram twice per day tapered over 6 months, and mycophenolate mofetil, at a dose of 15 mg per kilogram twice a day, started on the first day after transplantation and discontinued on day 28 after transplantation [20].