Average (∀SEM) final H-reflex size (average for final 10 days as % of initial size) for intact rats, CST-transected rats, and contralateral SMC-ablated rats after continued-control, HRup, or HRdown mode exposure. Continued control-mode exposure has no significant effect in any group. In intact rats, the HRup and HRdown modes have mode-appropriate effects. In CST rats, the HRup and HRdown modes have no significant effect. In cSMC rats, the HRup mode has no significant effect, while the HRdown mode actually increases H-reflex size. Asterisks indicate significant differences from initial size (***P < 0.001; **P < 0.005 by paired t-test).