TABLE 1.
terminal groupa | no. of atoms per dendrimer | mass (kDa) | charge (e) | |
---|---|---|---|---|
G3–NH3+ | –NH3+ | 1124 | 6.94 | +32 |
G3–Ac | –NHCOCH3 | 1252 | 8.25 | 0 |
G3–COO– | –NHCOCH2CH2COO– | 1412 | 10.1 | –32 |
All 32 primary amines of each G3 PAMAM dendrimer are converted to one of these three terminal groups, giving the dendrimers a +32e, 0, or –32e net charge.