Fig. 3.

Phylogeny generated using full-length MyHC sequences from humans (using cf MyHC16 to replace hMyHC16) and X. tropicalis. The major clades include the MyHC7b/MyHC15 (node A) group, the cardiac/fast skeletal group (node B), and MyHC16. The cardiac/fast skeletal group splits into the cardiac (node C) and fast-skeletal groups (Node D). The tropicalis fast skeletal isoforms form a single clade (node E). This clade subdivides by both array and temporal expression into adult and larval subgroups. Posterior probabilities are given as internal nodes, and all non-Xenopus sequences are listed in Supplementary material