Table 2.
Pro-inflammatory genes differentially regulated by obovatol
| Gene name | Fold change (LPS vs. control) | Fold change (obovatol+LPS vs. control) | Gene description |
|---|---|---|---|
| MCP-1 | 3.42 | 0.71 | Monocyte chemotactic protein 1 (CCL 2) |
| MCP-3 | 3.58 | 0.86 | Monocyte chemotactic protein 3 (CCL 7) |
| IP10 | 9.35 | 2.94 | Chemokine (C-X-C motif) ligand 10 (CXCL 10) |
| MIP-2α | 10.19 | 4.24 | Chemokine (C-X-C motif) ligand 2 (CXCL 2) |
| MIP-1β | 3.14 | 1.31 | Chemokine (C-X-C motif) ligand 4 (CXCL 4) |
| IL-1β | 2.26 | 1.02 | Interleukin 1β |
| MCP-5 | 2.12 | 1.10 | Monocyte chemotactic protein 5 (CCL 12) |
| TNFα | 2.28 | 1.26 | Tumour necrosis factor |
| MIP-1 | 2.02 | 1.18 | Chemokine (C-C motif) ligand 3 (CCL 3) |
IL-1, interleukin 1; IP10, interferon-inducible protein 10; MCP, monocyte chemotactic protein; MIP, macrophage inflammatory protein; TNF, tumour necrosis factor.