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Associations between rs4939827 and rs12953717 and risk of colon cancer
| Controls |
Cases |
||
|---|---|---|---|
| n | n | OR* (95% CI) | |
| rs4939827 | |||
| TT | 503 | 457 | 1.00 |
| TC | 992 | 773 | 0.86 (0.73–1.01) |
| CC | 492 | 360 | 0.77 (0.64–0.93) |
| P trend | <0.01 | ||
| rs12953717 | |||
| CC | 676 | 503 | 1.00 |
| CT | 928 | 754 | 1.09 (0.94–1.28) |
| TT | 327 | 332 | 1.38 (1.13–1.68) |
| P trend | <0.01 | ||
Risk estimates adjusted for age, center, race, sex, BMI, long-term activity level, average number of cigarettes per day, recent aspirin/NSAID use, dietary calcium, and energy intake.
