Table 2.
NF-κB signaling pathway (positive regulators of NF-κB activation cascade, NF-κB subunits, and cytosolic inhibitors of NF-κB)
| Gene name | Gene symbol | Ratio | NFkB target |
|---|---|---|---|
| NF-κB activation cascade | |||
| Tumor necrosis factor receptor superfamily, member 10b | TNFRSF10B | 3.62 | Yes |
| Receptor-interacting serine-threonine kinase 2 | RIPK2 | 4.12 | Yes |
| Baculoviral IAP repeat-containing 2 | BIRC2 | 5.75 | Yes |
| Tumor necrosis factor receptor superfamily, member 1A | TNFRSF1A | 2.16 | No |
| Tumor necrosis factor (TNF superfamily, member 2) | TNF | 8.81 | Yes |
| CD40 molecule, TNF receptor superfamily member 5 | CD40 | 6.35 | Yes |
| B-cell CLL/lymphoma 10 | BCL10 | 2.87 | Yes |
| TRAF 3 interacting protein 2 | TRAF3IP2 | 3.1 | No |
| CASP8 and FADD-like apoptosis regulator | CFLAR | 4.7 | Yes |
| Sequestosome 1 | SQSTM1 | 2.12 | Yes |
| NF-κB subunits | |||
| Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 (p105) | NFKB1 | 8.28 | Yes |
| Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100) | NFKB2 | 8.27 | Yes |
| V-rel reticuloendotheliosis viral oncogene homolog (avian) | cREL | 10.59 | Yes |
| V-rel reticuloendotheliosis viral oncogene homolog B | RELB | 11.56 | Yes |
| NF-κB inhibitory proteins | |||
| IKBα | NFKBIA | 21.61 | Yes |
| IKBϵ | NFKBIE | 3.62 | Yes |