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. Author manuscript; available in PMC: 2010 Aug 23.
Published in final edited form as: Muscle Nerve. 2009 Aug;40(2):279–286. doi: 10.1002/mus.21371

Figure 1.

Figure 1

RT-PCR results of mRNA isolated from limb muscles of mice with EAMG. A. Increased mRNA expression of AChR-α1 in muscle homogenates from EAMG mice compared to control animals. B. Enhanced expression of AChR-α1 transcript is most prominent in mice with more severe EAMG. C. RT-PCR results using primers designed to detect the presence of the P3A exon. Two AChR-α1 isoforms are clearly detected in human muscle tissue (H1, H2). However, a single isoform is expressed in the C2C12 mouse skeletal muscle cell line (C1, C2) and in muscle tissue from two mice with EAMG (M1, M2).