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. Author manuscript; available in PMC: 2011 Jul 12.
Published in final edited form as: J Comb Chem. 2010 Jul 12;12(4):491–496. doi: 10.1021/cc100029y

Figure 6.

Figure 6

FRET screening of 1,4-disubstituted 1,2,3-triazole binding affinity for model RNAs AM1A and C11U. The relative fluorescence intensity change ΔF was calculated by ΔF=[(F−F0)/F0]*100, where F is the fluorescence intensity with ligand and F0 is without ligand at 585 nm upon excitation at 467 nm. All of the compounds were tested at a final concentration of 10 µM.