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. 2010 Aug 23;5(8):e12333. doi: 10.1371/journal.pone.0012333

Figure 1. NAC increases striatal area occupied by TH-positive terminals in SNCA-overexpressing mice at 12 months of age.

Figure 1

A–D. Representative images of TH-immunostained 30 µm sections of alanine or NAC-treated wild-type or transgenic mouse striatum. A. Wild-type, alanine treated; B. Wild-type, NAC treated; C. Transgenic, alanine treated; D. Transgenic, NAC treated. E. Density of TH-positive terminals in the striatum of alanine or NAC-treated wild-type or transgenic mouse striatum. F. Density of DAT-positive terminals in the striatum of alanine or NAC-treated wild-type or transgenic mouse striatum. Data in E and F were analyzed using a 2-tailed Student's t-test. All relevant statistically significant comparisons are indicated on the graph. WT ALA N = 4, WT NAC  = 6, TG ALA  = 4, TG NAC  = 3.